Billy Lee’s side will face the All-Ireland runners up from the past two seasons on the weekend of June 9/10 at the Gaelic Grounds in a game that should draw a bumper crowd to the Ennis Road venue.
Mayo will be hot favourites to see off Division 4 side Limerick who were comprehensively beaten by Clare in the Munster Championship.
The game represents the first Championship meeting between the sides since 2002, where Mayo ran out one-point winners in round three of the qualifiers at Hyde Park.
Fixture details for the game will be confirmed by the CCCC on Tuesday afternoon.
It will be a return to the Gaelic Grounds for Mayo after their 2014 All-Ireland semi-final replay loss to Kerry at the venue.
The Draw (Sides on the left have home advantage) :
Derry v Kildare
Meath v Tyrone
London v Louth
Wicklow v Cavan
Offaly v Antrim
Limerick v Mayo
Westmeath v Armagh
Wexford v Waterford