Joe Schmidt has included 6 Munster players in his match day 23 to take on the USA.
Schmidt has handed exciting young Ulster back Jacob Stockdale his first Test start against the United States at Red Bull Arena in New Jersey on Saturday.
Shorn of 11 frontline players away on duty with the British and Irish Lions in New Zealand, Schmidt has named a youthful line-up with a further four players poised to win their first caps from the bench.
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Connacht hooker Dave Heffernan, Leinster pair Andrew Porter and James Ryan, and Munster centre Rory Scannell are all set to make their international debuts having been named among the replacements.
Stockdale, 21, has been in superb form for Ulster this season, scoring nine tries in the Guinness PRO12, having starred for the Ireland Under-20 side which reached the Junior World Championship final last summer.
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“We think that he’s someone who’s got great potential and we want to see what he can bring when the pressure comes on,” said Schmidt at Ireland’s team base in New York.
Porter, who only made the switch from loosehead prop to tighthead in recent months, will provide cover from the bench alongside 21-year-old second row Ryan, who has yet to make a senior appearance for Leinster.
Rookie hooker Heffernan will provide explosive impact from the bench while Scannell is coming off an impressive campaign with Munster.
“I think the young guys were impressive in the (U20) World Cup,” Schmidt said on the trio of Stockdale, Porter and Ryan.
“It’s an opportunity to build the base and those guys can help form that with performances in the next three weeks. It really is about building the base.
“You get to learn a bit more about them when they come into camp.”
Munster stalwart Simon Zebo will provide plenty of experience from the bench having suffered a couple of knocks in training earlier this week.